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TonEBP/NFAT5 Stimulates Transcription of HSP70 in Response to Hypertonicity

While hyperosmolality of the kidney medulla is essential for urinary concentration, it imposes a great deal of stress. Cells in the renal medulla adapt to the stress of hypertonicity (hyperosmotic salt) by accumulating organic osmolytes. Tonicity-responsive enhancer (TonE) binding protein (TonEBP) (...

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Autori principali: Woo, Seung Kyoon, Lee, Sang Do, Na, Ki Young, Park, Won Kun, Kwon, H. Moo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC133967/
https://ncbi.nlm.nih.gov/pubmed/12138186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.16.5753-5760.2002
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