TERRA RNA antagonizes ATRX and protects telomeres

Through an integration of genomic and proteomic approaches to advance understanding of long noncoding RNAs, we investigate the function of the telomeric transcript, TERRA. By identifying thousands of TERRA target sites in the mouse genome, we demonstrate that TERRA can bind both in cis to telomeres...

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Publicat a:Cell
Autors principals: Chu, Hsueh-Ping, Cifuentes-Rojas, Catherine, Kesner, Barry, Aeby, Eric, Lee, Hun-goo, Wei, Chunyao, Oh, Hyun Jung, Boukhali, Myriam, Haas, Wilhelm, Lee, Jeannie T.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552367/
https://ncbi.nlm.nih.gov/pubmed/28666128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.06.017
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