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The role of co-opted ESCRT proteins and lipid factors in protection of tombusviral double-stranded RNA replication intermediate against reconstituted RNAi in yeast

Reconstituted antiviral defense pathway in surrogate host yeast is used as an intracellular probe to further our understanding of virus-host interactions and the role of co-opted host factors in formation of membrane-bound viral replicase complexes in protection of the viral RNA against ribonuclease...

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Publicat a:PLoS Pathog
Autors principals: Kovalev, Nikolay, Inaba, Jun-ichi, Li, Zhenghe, Nagy, Peter D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552349/
https://ncbi.nlm.nih.gov/pubmed/28759634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006520
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