ATP Maintenance via Two Types of ATP Regulators Mitigates Pathological Phenotypes in Mouse Models of Parkinson's Disease

Parkinson's disease is assumed to be caused by mitochondrial dysfunction in the affected dopaminergic neurons in the brain. We have recently created small chemicals, KUSs (Kyoto University Substances), which can reduce cellular ATP consumption. By contrast, agonistic ligands of ERRs (estrogen r...

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Detaylı Bibliyografya
Yayımlandı:EBioMedicine
Asıl Yazarlar: Nakano, Masaki, Imamura, Hiromi, Sasaoka, Norio, Yamamoto, Masamichi, Uemura, Norihito, Shudo, Toshiyuki, Fuchigami, Tomohiro, Takahashi, Ryosuke, Kakizuka, Akira
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552266/
https://ncbi.nlm.nih.gov/pubmed/28780078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.07.024
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