Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling

Hepatitis C virus (HCV) infects 200 million people globally, and 60–80% of cases persist as a chronic infection that will progress to cirrhosis and liver cancer in 2–10% of patients(1–3). We recently demonstrated that HCV induces aberrant expression of two host microRNAs (miRNAs), miR-208b and miR-4...

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Publicado no:Nat Med
Main Authors: Jarret, Abigail, McFarland, Adelle P, Horner, Stacy M, Kell, Alison, Schwerk, Johannes, Hong, MeeAe, Badil, Samantha, Joslyn, Rochelle C, Baker, Darren P, Carrington, Mary, Hagedorn, Curt H, Gale, Michael, Savan, Ram
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551900/
https://ncbi.nlm.nih.gov/pubmed/27841874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4211
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