IFNL3 (IL28B) favorable genotype escapes hepatitis C virus-induced microRNAs and mRNA decay

The IFNL3 (IL28B) gene has received immense attention in the hepatitis C virus (HCV) field as multiple independent genome-wide association studies identified a strong association between polymorphisms near the IFNL3 gene and HCV clearance. However, the mechanism underlying this association has remai...

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Detalhes bibliográficos
Main Authors: McFarland, Adelle P., Horner, Stacy M., Jarret, Abigail, Joslyn, Rochelle C., Bindewald, Eckart, Shapiro, Bruce A., Delker, Don A., Hagedorn, Curt, Carrington, Mary, Gale, Michael, Savan, Ram
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183367/
https://ncbi.nlm.nih.gov/pubmed/24241692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2758
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