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Convergent Evolution of Escape from Hepaciviral Antagonism in Primates

The ability to mount an interferon response on sensing viral infection is a critical component of mammalian innate immunity. Several viruses directly antagonize viral sensing pathways to block activation of the host immune response. Here, we show that recurrent viral antagonism has shaped the evolut...

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Detalhes bibliográficos
Main Authors: Patel, Maulik R., Loo, Yueh-Ming, Horner, Stacy M., Gale, Michael, Malik, Harmit S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302847/
https://ncbi.nlm.nih.gov/pubmed/22427742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001282
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