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Convergent Evolution of Escape from Hepaciviral Antagonism in Primates

The ability to mount an interferon response on sensing viral infection is a critical component of mammalian innate immunity. Several viruses directly antagonize viral sensing pathways to block activation of the host immune response. Here, we show that recurrent viral antagonism has shaped the evolut...

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Bibliografiska uppgifter
Huvudupphovsmän: Patel, Maulik R., Loo, Yueh-Ming, Horner, Stacy M., Gale, Michael, Malik, Harmit S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302847/
https://ncbi.nlm.nih.gov/pubmed/22427742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001282
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