Interferon lambda 4 expression is suppressed by the host during viral infection

Interferon (IFN) lambdas are critical antiviral effectors in hepatic and mucosal infections. Although IFNλ1, IFNλ2, and IFNλ3 act antiviral, genetic association studies have shown that expression of the recently discovered IFNL4 is detrimental to hepatitis C virus (HCV) infection through a yet unkno...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Hong, MeeAe, Schwerk, Johannes, Lim, Chrissie, Kell, Alison, Jarret, Abigail, Pangallo, Joseph, Loo, Yueh-Ming, Liu, Shuanghu, Hagedorn, Curt H., Gale, Michael, Savan, Ram
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110018/
https://ncbi.nlm.nih.gov/pubmed/27799623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160437
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