Interferon lambda 4 expression is suppressed by the host during viral infection

Interferon (IFN) lambdas are critical antiviral effectors in hepatic and mucosal infections. Although IFNλ1, IFNλ2, and IFNλ3 act antiviral, genetic association studies have shown that expression of the recently discovered IFNL4 is detrimental to hepatitis C virus (HCV) infection through a yet unkno...

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Vydáno v:J Exp Med
Hlavní autoři: Hong, MeeAe, Schwerk, Johannes, Lim, Chrissie, Kell, Alison, Jarret, Abigail, Pangallo, Joseph, Loo, Yueh-Ming, Liu, Shuanghu, Hagedorn, Curt H., Gale, Michael, Savan, Ram
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110018/
https://ncbi.nlm.nih.gov/pubmed/27799623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160437
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