Interferon lambda 4 expression is suppressed by the host during viral infection

Interferon (IFN) lambdas are critical antiviral effectors in hepatic and mucosal infections. Although IFNλ1, IFNλ2, and IFNλ3 act antiviral, genetic association studies have shown that expression of the recently discovered IFNL4 is detrimental to hepatitis C virus (HCV) infection through a yet unkno...

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Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Hong, MeeAe, Schwerk, Johannes, Lim, Chrissie, Kell, Alison, Jarret, Abigail, Pangallo, Joseph, Loo, Yueh-Ming, Liu, Shuanghu, Hagedorn, Curt H., Gale, Michael, Savan, Ram
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2016
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110018/
https://ncbi.nlm.nih.gov/pubmed/27799623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160437
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