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Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor

Mechanisms and signals that regulate transcriptional coactivators are still largely unknown. Here we provide genetic evidence for a repressor that interacts with and regulates the nuclear receptor coactivator PGC-1. Association with the repressor requires a PGC-1 protein interface that is similar to...

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Autori principali: Knutti, Darko, Kressler, Dieter, Kralli, Anastasia
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC55518/
https://ncbi.nlm.nih.gov/pubmed/11481440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171184698
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