Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor

Mechanisms and signals that regulate transcriptional coactivators are still largely unknown. Here we provide genetic evidence for a repressor that interacts with and regulates the nuclear receptor coactivator PGC-1. Association with the repressor requires a PGC-1 protein interface that is similar to...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Knutti, Darko, Kressler, Dieter, Kralli, Anastasia
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55518/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11481440/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.171184698
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