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Cell cycle–dependent spatial segregation of telomerase from sites of DNA damage
Telomerase can generate a novel telomere at DNA double-strand breaks (DSBs), an event called de novo telomere addition. How this activity is suppressed remains unclear. Combining single-molecule imaging and deep sequencing, we show that the budding yeast telomerase RNA (TLC1 RNA) is spatially segreg...
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| Vydáno v: | J Cell Biol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551704/ https://ncbi.nlm.nih.gov/pubmed/28637749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201610071 |
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