miR-99 regulates normal and malignant hematopoietic stem cell self-renewal

The microRNA-99 (miR-99) family comprises a group of broadly conserved microRNAs that are highly expressed in hematopoietic stem cells (HSCs) and acute myeloid leukemia stem cells (LSCs) compared with their differentiated progeny. Herein, we show that miR-99 regulates self-renewal in both HSCs and L...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Khalaj, Mona, Woolthuis, Carolien M., Hu, Wenhuo, Durham, Benjamin H., Chu, S. Haihua, Qamar, Sarah, Armstrong, Scott A., Park, Christopher Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551568/
https://ncbi.nlm.nih.gov/pubmed/28733386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161595
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