Ablation of miR-146b in mice causes hematopoietic malignancy

Excessive and constitutive activation of nuclear factor-κB (NF-κB) leads to abnormal cell proliferation and differentiation, leading to the development of malignant tumors, including lymphoma. MicroRNA 146a (miR-146a) and miR-146b, both of which carry an identical seed sequence, have been shown to c...

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Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Mitsumura, Takahiro, Ito, Yoshiaki, Chiba, Tomoki, Matsushima, Takahide, Kurimoto, Ryota, Tanaka, Yoko, Kato, Tomomi, Uchida, Keisuke, Ito, Takashi, Yamamoto, Kouhei, Eishi, Yoshinobu, Kitagawa, Masanobu, Miyazaki, Yasunari, Inase, Naohiko, Asahara, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2018
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290096/
https://ncbi.nlm.nih.gov/pubmed/30530754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018017954
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