The tRNA pseudouridine synthase TruB1 regulates the maturation of let‐7 miRNA

Let‐7 is an evolutionary conserved microRNA that mediates post‐transcriptional gene silencing to regulate a wide range of biological processes, including development, differentiation, and tumor suppression. Let‐7 biogenesis is tightly regulated by several RNA‐binding proteins, including Lin28A/B, wh...

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Vydáno v:EMBO J
Hlavní autoři: Kurimoto, Ryota, Chiba, Tomoki, Ito, Yoshiaki, Matsushima, Takahide, Yano, Yuki, Miyata, Kohei, Yashiro, Yuka, Suzuki, Tsutomu, Tomita, Kozo, Asahara, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560213/
https://ncbi.nlm.nih.gov/pubmed/32926445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104708
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