Cathepsin-S degraded decorin are elevated in fibrotic lung disorders – development and biological validation of a new serum biomarker

BACKGROUND: Decorin is one of the most abundant proteoglycans of the extracellular matrix and is mainly secreted and deposited in the interstitial matrix by fibroblasts where it plays an important role in collagen turnover and tissue homeostasis. Degradation of decorin might disturb normal tissue ho...

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Detaylı Bibliyografya
Yayımlandı:BMC Pulm Med
Asıl Yazarlar: Kehlet, S.N., Bager, C.L., Willumsen, N., Dasgupta, B., Brodmerkel, C., Curran, M., Brix, S., Leeming, D.J., Karsdal, M. A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550991/
https://ncbi.nlm.nih.gov/pubmed/28793886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-017-0455-x
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