Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non–Small Cell Lung Cancer

Loss of basement membrane (BM) integrity is typically associated with cancer. Nidogen-1 is an essential component of the BM. Nidogen-1 is a substrate for cathepsin-S (CatS) which is released into the tumor microenvironment. Measuring nidogen-1 degraded by CatS may therefore have biomarker potential...

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Publicat a:Neoplasia
Autors principals: Willumsen, Nicholas, Bager, Cecilie L., Leeming, Diana J., Bay-Jensen, Anne-Christine, Karsdal, Morten A.
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2017
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344320/
https://ncbi.nlm.nih.gov/pubmed/28282545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.01.008
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