Edaravone suppresses retinal ganglion cell death in a mouse model of normal tension glaucoma

Glaucoma, one of the leading causes of irreversible blindness, is characterized by progressive degeneration of optic nerves and retinal ganglion cells (RGCs). In the mammalian retina, excitatory amino-acid carrier 1 (EAAC1) is expressed in neural cells, including RGCs. Loss of EAAC1 leads to RGC deg...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Akaiwa, Kei, Namekata, Kazuhiko, Azuchi, Yuriko, Guo, Xiaoli, Kimura, Atsuko, Harada, Chikako, Mitamura, Yoshinori, Harada, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550882/
https://ncbi.nlm.nih.gov/pubmed/28703795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.341
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