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Edaravone suppresses retinal ganglion cell death in a mouse model of normal tension glaucoma

Glaucoma, one of the leading causes of irreversible blindness, is characterized by progressive degeneration of optic nerves and retinal ganglion cells (RGCs). In the mammalian retina, excitatory amino-acid carrier 1 (EAAC1) is expressed in neural cells, including RGCs. Loss of EAAC1 leads to RGC deg...

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Foilsithe in:Cell Death Dis
Main Authors: Akaiwa, Kei, Namekata, Kazuhiko, Azuchi, Yuriko, Guo, Xiaoli, Kimura, Atsuko, Harada, Chikako, Mitamura, Yoshinori, Harada, Takayuki
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550882/
https://ncbi.nlm.nih.gov/pubmed/28703795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.341
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