Edaravone suppresses retinal ganglion cell death in a mouse model of normal tension glaucoma

Glaucoma, one of the leading causes of irreversible blindness, is characterized by progressive degeneration of optic nerves and retinal ganglion cells (RGCs). In the mammalian retina, excitatory amino-acid carrier 1 (EAAC1) is expressed in neural cells, including RGCs. Loss of EAAC1 leads to RGC deg...

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Vydáno v:Cell Death Dis
Hlavní autoři: Akaiwa, Kei, Namekata, Kazuhiko, Azuchi, Yuriko, Guo, Xiaoli, Kimura, Atsuko, Harada, Chikako, Mitamura, Yoshinori, Harada, Takayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550882/
https://ncbi.nlm.nih.gov/pubmed/28703795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.341
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