Autophagy inhibition reduces chemoresistance and tumorigenic potential of human ovarian cancer stem cells

Epithelial ovarian cancer (EOC) is one of the most malignant gynecological tumors with a high mortality rate owing to tumor relapse after anticancer therapies. It is widely accepted that a rare tumor cell population, known as cancer stem cells (CSC), is responsible for tumor progression and relapse;...

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Vydáno v:Cell Death Dis
Hlavní autoři: Pagotto, Anna, Pilotto, Giorgia, Mazzoldi, Elena Laura, Nicoletto, Maria Ornella, Frezzini, Simona, Pastò, Anna, Amadori, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550872/
https://ncbi.nlm.nih.gov/pubmed/28726781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.327
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