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Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway

Sonic hedgehog (Shh) signaling is essential for proliferation of cerebellar granule cell progenitors (GCPs) and its misregulation is linked to various disorders, including cerebellar cancer medulloblastoma. The effects of Shh pathway are mediated by the Gli family of transcription factors, which con...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Quaranta, Roberta, Pelullo, Maria, Zema, Sabrina, Nardozza, Francesca, Checquolo, Saula, Lauer, Dieter Matthias, Bufalieri, Francesca, Palermo, Rocco, Felli, Maria Pia, Vacca, Alessandra, Talora, Claudio, Di Marcotullio, Lucia, Screpanti, Isabella, Bellavia, Diana
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550871/
https://ncbi.nlm.nih.gov/pubmed/28726779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.326
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