Poly(ADP-ribose) polymerase auto-modification and interaction with DNA: electron microscopic visualization.

The interaction between purified calf thymus poly(ADP-ribose) polymerase and its activating co-purified DNA (sDNA) was investigated by electron microscopy. We have shown that the enzyme-DNA complex possesses a nucleosome-like structure. The enzyme-bound DNA (sDNA) was found to be enriched in single-...

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Bibliografiske detaljer
Main Authors: de Murcia, G, Jongstra-Bilen, J, Ittel, M E, Mandel, P, Delain, E
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC555058/
https://ncbi.nlm.nih.gov/pubmed/6313345
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