Poly(ADP-ribose) polymerase auto-modification and interaction with DNA: electron microscopic visualization.

The interaction between purified calf thymus poly(ADP-ribose) polymerase and its activating co-purified DNA (sDNA) was investigated by electron microscopy. We have shown that the enzyme-DNA complex possesses a nucleosome-like structure. The enzyme-bound DNA (sDNA) was found to be enriched in single-...

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Bibliographic Details
Published in:EMBO J
Main Authors: de Murcia, G, Jongstra-Bilen, J, Ittel, M E, Mandel, P, Delain, E
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1983
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC555058/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6313345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1983.tb01460.x
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