Poly(ADP-ribose) polymerase auto-modification and interaction with DNA: electron microscopic visualization.

The interaction between purified calf thymus poly(ADP-ribose) polymerase and its activating co-purified DNA (sDNA) was investigated by electron microscopy. We have shown that the enzyme-DNA complex possesses a nucleosome-like structure. The enzyme-bound DNA (sDNA) was found to be enriched in single-...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	de Murcia, G, Jongstra-Bilen, J, Ittel, M E, Mandel, P, Delain, E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1983
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC555058/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6313345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1983.tb01460.x
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