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Non-uniform self-assembly: On the anisotropic architecture of α-synuclein supra-fibrillar aggregates

Although the function of biopolymer hydrogels in nature depends on structural anisotropy at mesoscopic length scales, the self-assembly of such anisotropic structures in vitro is challenging. Here we show that fibrils of the protein α-synuclein spontaneously self-assemble into structurally anisotrop...

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Publicat a:Sci Rep
Autors principals: Semerdzhiev, Slav A., Shvadchak, Volodymyr V., Subramaniam, Vinod, Claessens, Mireille M. A. E.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550477/
https://ncbi.nlm.nih.gov/pubmed/28794461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06532-1
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