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Vitamin B(12) as a carrier of peptide nucleic acid (PNA) into bacterial cells

Short modified oligonucleotides targeted at bacterial DNA or RNA could serve as antibacterial agents provided that they are efficiently taken up by bacterial cells. However, the uptake of such oligonucleotides is hindered by the bacterial cell wall. To overcome this problem, oligomers have been atta...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Równicki, Marcin, Wojciechowska, Monika, Wierzba, Aleksandra J., Czarnecki, Jakub, Bartosik, Dariusz, Gryko, Dorota, Trylska, Joanna
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550456/
https://ncbi.nlm.nih.gov/pubmed/28794451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08032-8
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