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Vitamin B(12) as a carrier of peptide nucleic acid (PNA) into bacterial cells

Short modified oligonucleotides targeted at bacterial DNA or RNA could serve as antibacterial agents provided that they are efficiently taken up by bacterial cells. However, the uptake of such oligonucleotides is hindered by the bacterial cell wall. To overcome this problem, oligomers have been atta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Równicki, Marcin, Wojciechowska, Monika, Wierzba, Aleksandra J., Czarnecki, Jakub, Bartosik, Dariusz, Gryko, Dorota, Trylska, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550456/
https://ncbi.nlm.nih.gov/pubmed/28794451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08032-8
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