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Neonatal leptin treatment reverses the bone-suppressive effects of maternal undernutrition in adult rat offspring

Alterations in the early life environment, including maternal undernutrition (UN) during pregnancy, can lead to increased risk of metabolic and cardiovascular disorders in offspring. Leptin treatment of neonates born to UN rats reverses the programmed metabolic phenotype, but the possible benefits o...

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Publicado en:Sci Rep
Autores principales: Firth, Elwyn C., Gamble, Greg D., Cornish, Jillian, Vickers, Mark H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550441/
https://ncbi.nlm.nih.gov/pubmed/28794412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07500-5
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