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Neonatal leptin treatment reverses the bone-suppressive effects of maternal undernutrition in adult rat offspring

Alterations in the early life environment, including maternal undernutrition (UN) during pregnancy, can lead to increased risk of metabolic and cardiovascular disorders in offspring. Leptin treatment of neonates born to UN rats reverses the programmed metabolic phenotype, but the possible benefits o...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Firth, Elwyn C., Gamble, Greg D., Cornish, Jillian, Vickers, Mark H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550441/
https://ncbi.nlm.nih.gov/pubmed/28794412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07500-5
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