Neonatal leptin treatment reverses the bone-suppressive effects of maternal undernutrition in adult rat offspring

Alterations in the early life environment, including maternal undernutrition (UN) during pregnancy, can lead to increased risk of metabolic and cardiovascular disorders in offspring. Leptin treatment of neonates born to UN rats reverses the programmed metabolic phenotype, but the possible benefits o...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Firth, Elwyn C., Gamble, Greg D., Cornish, Jillian, Vickers, Mark H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550441/
https://ncbi.nlm.nih.gov/pubmed/28794412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07500-5
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