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Neonatal leptin treatment reverses the bone-suppressive effects of maternal undernutrition in adult rat offspring

Alterations in the early life environment, including maternal undernutrition (UN) during pregnancy, can lead to increased risk of metabolic and cardiovascular disorders in offspring. Leptin treatment of neonates born to UN rats reverses the programmed metabolic phenotype, but the possible benefits o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Firth, Elwyn C., Gamble, Greg D., Cornish, Jillian, Vickers, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550441/
https://ncbi.nlm.nih.gov/pubmed/28794412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07500-5
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