Dynamic hyper-editing underlies temperature adaptation in Drosophila

In Drosophila, A-to-I editing is prevalent in the brain, and mutations in the editing enzyme ADAR correlate with specific behavioral defects. Here we demonstrate a role for ADAR in behavioral temperature adaptation in Drosophila. Although there is a higher level of editing at lower temperatures, at...

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Udgivet i:PLoS Genet
Main Authors: Buchumenski, Ilana, Bartok, Osnat, Ashwal-Fluss, Reut, Pandey, Varun, Porath, Hagit T., Levanon, Erez Y., Kadener, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550009/
https://ncbi.nlm.nih.gov/pubmed/28746393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006931
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