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An in vivo strategy for knockdown of circular RNAs

Exonic circular RNAs (circRNAs) are highly abundant RNAs generated mostly from exons of protein-coding genes. Assaying the functions of circRNAs is not straightforward as common approaches for circRNA depletion tend to also alter the levels of mRNAs generated from the hosting gene. Here we describe...

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Dettagli Bibliografici
Pubblicato in:Cell Discov
Autori principali: Pamudurti, Nagarjuna Reddy, Patop, Ines Lucia, Krishnamoorthy, Aishwarya, Ashwal-Fluss, Reut, Bartok, Osnat, Kadener, Sebastian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Singapore 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417560/
https://ncbi.nlm.nih.gov/pubmed/32818061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-0182-y
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