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An in vivo strategy for knockdown of circular RNAs

Exonic circular RNAs (circRNAs) are highly abundant RNAs generated mostly from exons of protein-coding genes. Assaying the functions of circRNAs is not straightforward as common approaches for circRNA depletion tend to also alter the levels of mRNAs generated from the hosting gene. Here we describe...

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Detalles Bibliográficos
Publicado en:Cell Discov
Main Authors: Pamudurti, Nagarjuna Reddy, Patop, Ines Lucia, Krishnamoorthy, Aishwarya, Ashwal-Fluss, Reut, Bartok, Osnat, Kadener, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado: Springer Singapore 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417560/
https://ncbi.nlm.nih.gov/pubmed/32818061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-0182-y
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