Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement

Syk and ZAP-70 nonreceptor protein tyrosine kinases (PTKs) are essential elements in several cascades coupling immune receptors to intracellular responses. The critical role of these kinases in promoting the propagation of intracellular signaling requires a tight regulation of their activity, thus t...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Paolini, Rossella, Molfetta, Rosa, Piccoli, Mario, Frati, Luigi, Santoni, Angela
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55500/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11493682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.161298098
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