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Polyfluoroarylation of Oxazolones: Access to Non-Natural Fluorinated Amino Acids

Herein, conditions are provided for the formation and use of the oxazolone enolate for the nucleophilic substitution of highly fluorinated (hetero) arenes, which after unmasking yield highly fluorinated non-natural amino acids and derivatives. In addition, the properties and chemical behavior of thi...

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Sparad:
Bibliografiska uppgifter
I publikationen:Chem Commun (Camb)
Huvudupphovsmän: Teegardin, Kip A., Weaver, Jimmie D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549939/
https://ncbi.nlm.nih.gov/pubmed/28357423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc01606a
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