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Polyfluoroarylation of Oxazolones: Access to Non-Natural Fluorinated Amino Acids

Herein, conditions are provided for the formation and use of the oxazolone enolate for the nucleophilic substitution of highly fluorinated (hetero) arenes, which after unmasking yield highly fluorinated non-natural amino acids and derivatives. In addition, the properties and chemical behavior of thi...

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Pubblicato in:Chem Commun (Camb)
Autori principali: Teegardin, Kip A., Weaver, Jimmie D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549939/
https://ncbi.nlm.nih.gov/pubmed/28357423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc01606a
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