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Polyfluoroarylation of Oxazolones: Access to Non-Natural Fluorinated Amino Acids

Herein, conditions are provided for the formation and use of the oxazolone enolate for the nucleophilic substitution of highly fluorinated (hetero) arenes, which after unmasking yield highly fluorinated non-natural amino acids and derivatives. In addition, the properties and chemical behavior of thi...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Teegardin, Kip A., Weaver, Jimmie D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549939/
https://ncbi.nlm.nih.gov/pubmed/28357423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc01606a
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