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Polyfluoroarylation of Oxazolones: Access to Non-Natural Fluorinated Amino Acids

Herein, conditions are provided for the formation and use of the oxazolone enolate for the nucleophilic substitution of highly fluorinated (hetero) arenes, which after unmasking yield highly fluorinated non-natural amino acids and derivatives. In addition, the properties and chemical behavior of thi...

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Bibliografische gegevens
Gepubliceerd in:Chem Commun (Camb)
Hoofdauteurs: Teegardin, Kip A., Weaver, Jimmie D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549939/
https://ncbi.nlm.nih.gov/pubmed/28357423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc01606a
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