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Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins

DNA-dependent protein kinase (DNA-PK) acts through an essential relationship with DNA to participate in the regulation of multiple cellular processes. Yet the role of DNA as a cofactor in kinase activity remains to be completely elucidated. For example, although DNA-PK activity appears to be require...

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Библиографические подробности
Главные авторы: Soubeyrand, Sébastien, Torrance, Heather, Giffin, Ward, Gong, Wenrong, Schild-Poulter, Caroline, Haché, Robert J. G.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC55499/
https://ncbi.nlm.nih.gov/pubmed/11481441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171211398
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