Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins

DNA-dependent protein kinase (DNA-PK) acts through an essential relationship with DNA to participate in the regulation of multiple cellular processes. Yet the role of DNA as a cofactor in kinase activity remains to be completely elucidated. For example, although DNA-PK activity appears to be require...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Soubeyrand, Sébastien, Torrance, Heather, Giffin, Ward, Gong, Wenrong, Schild-Poulter, Caroline, Haché, Robert J. G.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2001
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55499/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11481441/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.171211398
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