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A Short Region of Connexin43 Reduces Human Glioma Stem Cell Migration, Invasion, and Survival through Src, PTEN, and FAK

Connexin43 (CX43), a protein that forms gap junction channels and hemichannels in astrocytes, is downregulated in high-grade gliomas. Its relevance for glioma therapy has been thoroughly explored; however, its positive effects on proliferation are counterbalanced by its effects on migration and inva...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Jaraíz-Rodríguez, Myriam, Tabernero, Ma Dolores, González-Tablas, María, Otero, Alvaro, Orfao, Alberto, Medina, Jose M., Tabernero, Arantxa
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549880/
https://ncbi.nlm.nih.gov/pubmed/28712848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.06.007
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