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Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes

Connexin43 (Cx43), the major protein forming gap junctions in astrocytes, is reduced in high-grade gliomas, where its ectopic expression exerts important effects, including the inhibition of the proto-oncogene tyrosine-protein kinase Src (c-Src). In this work we aimed to investigate the mechanism re...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: González-Sánchez, Ana, Jaraíz-Rodríguez, Myriam, Domínguez-Prieto, Marta, Herrero-González, Sandra, Medina, José M., Tabernero, Arantxa
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226550/
https://ncbi.nlm.nih.gov/pubmed/27391443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10454
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