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A cell-penetrating peptide based on the interaction between c-Src and connexin43 reverses glioma stem cell phenotype

Connexin43 (Cx43), the main gap junction channel-forming protein in astrocytes, is downregulated in malignant gliomas. These tumors are composed of a heterogeneous population of cells that include many with stem-cell-like properties, called glioma stem cells (GSCs), which are highly tumorigenic and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gangoso, E, Thirant, C, Chneiweiss, H, Medina, J M, Tabernero, A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040690/
https://ncbi.nlm.nih.gov/pubmed/24457967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.560
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