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Smoking-Dependent Distal-to-Proximal Repatterning of the Adult Human Small Airway Epithelium

Rationale: Small airways are the primary site of pathologic changes in chronic obstructive pulmonary disease (COPD), the major smoking-induced lung disorder. Objectives: On the basis of the concept of proximal–distal patterning that determines regional specialization of the airway epithelium during...

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Publicat a:Am J Respir Crit Care Med
Autors principals: Yang, Jing, Zuo, Wu-Lin, Fukui, Tomoya, Chao, IonWa, Gomi, Kazunori, Lee, Busub, Staudt, Michelle R., Kaner, Robert J., Strulovici-Barel, Yael, Salit, Jacqueline, Crystal, Ronald G., Shaykhiev, Renat
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549864/
https://ncbi.nlm.nih.gov/pubmed/28345955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201608-1672OC
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