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EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype

The airway epithelium of smokers acquires pathological phenotypes, including basal cell (BC) and/or goblet cell hyperplasia, squamous metaplasia, structural and functional abnormalities of ciliated cells, decreased number of secretoglobin (SCGB1A1)-expressing secretory cells, and a disordered juncti...

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Detalhes bibliográficos
Main Authors: Shaykhiev, Renat, Zuo, Wu-Lin, Chao, IonWa, Fukui, Tomoya, Witover, Bradley, Brekman, Angelika, Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718120/
https://ncbi.nlm.nih.gov/pubmed/23818594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303058110
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