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EGF-Amphiregulin Interplay in Airway Stem/Progenitor Cells Links the Pathogenesis of Smoking-Induced Lesions in the Human Airway Epithelium

The airway epithelium of cigarette smokers undergoes dramatic remodeling with hyperplasia of basal cells (BC) and mucus-producing cells, squamous metaplasia, altered ciliated cell differentiation and decreased junctional barrier integrity, relevant to chronic obstructive pulmonary disease and lung c...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Zuo, Wu-Lin, Yang, Jing, Gomi, Kazunori, Chao, IonWa, Crystal, Ronald G., Shaykhiev, Renat
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330845/
https://ncbi.nlm.nih.gov/pubmed/27709733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2512
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