Cellular DEAD-box RNA helicase DDX6 modulates interaction of miR-122 with the 5′ untranslated region of hepatitis C virus RNA

Hepatitis C virus (HCV) subverts the cellular DEAD-box RNA helicase DDX6 to promote virus infection. Using polysome gradient analysis and the subgenomic HCV Renilla reporter replicon genome, we determined that DDX6 does not affect HCV translation. Rather expression of the subgenomic HCV Renilla luci...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Biegel, Jason M., Henderson, Eric, Cox, Erica M., Bonenfant, Gaston, Netzband, Rachel, Kahn, Samantha, Eager, Rachel, Pager, Cara T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549679/
https://ncbi.nlm.nih.gov/pubmed/28456022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.04.014
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