Cellular DEAD-box RNA helicase DDX6 modulates interaction of miR-122 with the 5′ untranslated region of hepatitis C virus RNA

Hepatitis C virus (HCV) subverts the cellular DEAD-box RNA helicase DDX6 to promote virus infection. Using polysome gradient analysis and the subgenomic HCV Renilla reporter replicon genome, we determined that DDX6 does not affect HCV translation. Rather expression of the subgenomic HCV Renilla luci...

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Bibliografiske detaljer
Udgivet i:Virology
Main Authors: Biegel, Jason M., Henderson, Eric, Cox, Erica M., Bonenfant, Gaston, Netzband, Rachel, Kahn, Samantha, Eager, Rachel, Pager, Cara T.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549679/
https://ncbi.nlm.nih.gov/pubmed/28456022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.04.014
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