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FLT3 Ligand regulates thymic precursor cells and hematopoietic stem cells through interactions with CXCR4 and the marrow niche

Impaired immune reconstitution after hematopoietic stem cell transplantation (HSCT) is attributed in part to impaired thymopoiesis. Recent data suggest that precursor input may be a point of regulation for the thymus. We hypothesized that administration of FLT3 Ligand (FLT3L) would enhance thymopoie...

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Detalhes bibliográficos
Publicado no:Exp Hematol
Main Authors: Williams, Kirsten M., Moore, Amber R., Lucas, Philip J., Wang, Juin, Bare, Catherine V., Gress, Ronald E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549459/
https://ncbi.nlm.nih.gov/pubmed/28552733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2017.05.005
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