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FLT3 Ligand regulates thymic precursor cells and hematopoietic stem cells through interactions with CXCR4 and the marrow niche

Impaired immune reconstitution after hematopoietic stem cell transplantation (HSCT) is attributed in part to impaired thymopoiesis. Recent data suggest that precursor input may be a point of regulation for the thymus. We hypothesized that administration of FLT3 Ligand (FLT3L) would enhance thymopoie...

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Bibliografiske detaljer
Udgivet i:Exp Hematol
Main Authors: Williams, Kirsten M., Moore, Amber R., Lucas, Philip J., Wang, Juin, Bare, Catherine V., Gress, Ronald E.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549459/
https://ncbi.nlm.nih.gov/pubmed/28552733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2017.05.005
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