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The active site dynamics of 4-chlorobenzoyl-CoA dehalogenase

A molecular dynamics study was performed to compare the differences in the active-site dynamics of the wild-type and W137F mutant enzymes of 4-chlorobenzoyl-CoA dehalogenase. Only in the wild-type simulation are conformations formed between the catalytic Asp-145 and 4-chlorobenzoyl-CoA, which resemb...

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Detalhes bibliográficos
Main Authors: Lau, Edmond Y., Bruice, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55486/
https://ncbi.nlm.nih.gov/pubmed/11493680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161282698
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